The 2025 Nobel Prize in Medicine has been awarded jointly to American scientists Mary Brinkau, Fred Ramsdell, and Japanese researcher Shimon Sakaguchi.
The prize recognizes their groundbreaking work in discovering how to stop the human immune system from attacking itself, a mechanism known as peripheral immune tolerance.
According to the Nobel Committee, this discovery has opened new doors for treating cancer and autoimmune diseases. The researchers identified regulatory T cells, which act like “security guards” in the body by preventing immune cells from mistakenly attacking healthy tissues.
Speaking outside Osaka University, Sakaguchi described receiving the Nobel Prize as “a great honor and a moment of immense pride.”
Along with the honor, the winners will share 11 million Swedish kronor (about $1.2 million) and receive Nobel medals, traditionally presented by the King of Sweden.
Medical experts believe the findings of Brinkau, Ramsdell, and Sakaguchi will influence future research and offer hope for millions of patients worldwide battling autoimmune conditions and cancers.
Meanwhile, scientific breakthroughs and global challenges continue to shape the modern world. In a different context, Pakistan’s National Cyber Agency recently issued a warning about staying alert against new types of viruses targeting online systems. Read more here.
The Nobel recognition in 2025 not only highlights the importance of medical research but also underlines the global collaboration between American and Japanese scientists in advancing human health.
